1 00:00:00,000 --> 00:00:52,480 I 2 00:00:52,480 --> 00:00:52,490 3 00:00:52,490 --> 00:00:56,540 okay we're with you Franklin hello 4 00:00:56,540 --> 00:00:56,550 okay we're with you Franklin hello 5 00:00:56,550 --> 00:00:59,120 okay we're with you Franklin hello welcome to the space shuttle Columbia on 6 00:00:59,120 --> 00:00:59,130 welcome to the space shuttle Columbia on 7 00:00:59,130 --> 00:01:02,810 welcome to the space shuttle Columbia on this mission fts 75 we have spent the 8 00:01:02,810 --> 00:01:02,820 this mission fts 75 we have spent the 9 00:01:02,820 --> 00:01:05,000 this mission fts 75 we have spent the last several days conducting research in 10 00:01:05,000 --> 00:01:05,010 last several days conducting research in 11 00:01:05,010 --> 00:01:07,700 last several days conducting research in microgravity science one particular 12 00:01:07,700 --> 00:01:07,710 microgravity science one particular 13 00:01:07,710 --> 00:01:09,620 microgravity science one particular experiment which I wanted to mention to 14 00:01:09,620 --> 00:01:09,630 experiment which I wanted to mention to 15 00:01:09,630 --> 00:01:11,900 experiment which I wanted to mention to you distant world involved in the 16 00:01:11,900 --> 00:01:11,910 you distant world involved in the 17 00:01:11,910 --> 00:01:14,440 you distant world involved in the crystallization of proteins in 18 00:01:14,440 --> 00:01:14,450 crystallization of proteins in 19 00:01:14,450 --> 00:01:18,469 crystallization of proteins in weightlessness in the proteins are some 20 00:01:18,469 --> 00:01:18,479 weightlessness in the proteins are some 21 00:01:18,479 --> 00:01:20,330 weightlessness in the proteins are some of the most fundamental building blocks 22 00:01:20,330 --> 00:01:20,340 of the most fundamental building blocks 23 00:01:20,340 --> 00:01:24,680 of the most fundamental building blocks for lives on our planet Earth they also 24 00:01:24,680 --> 00:01:24,690 for lives on our planet Earth they also 25 00:01:24,690 --> 00:01:27,710 for lives on our planet Earth they also play a key role in the life cycle of 26 00:01:27,710 --> 00:01:27,720 play a key role in the life cycle of 27 00:01:27,720 --> 00:01:31,249 play a key role in the life cycle of disease they control for example 28 00:01:31,249 --> 00:01:31,259 disease they control for example 29 00:01:31,259 --> 00:01:33,440 disease they control for example critical functions like reproduction 30 00:01:33,440 --> 00:01:33,450 critical functions like reproduction 31 00:01:33,450 --> 00:01:38,330 critical functions like reproduction like growth and of course that now with 32 00:01:38,330 --> 00:01:38,340 like growth and of course that now with 33 00:01:38,340 --> 00:01:41,690 like growth and of course that now with this in mind and in their continuous war 34 00:01:41,690 --> 00:01:41,700 this in mind and in their continuous war 35 00:01:41,700 --> 00:01:44,960 this in mind and in their continuous war against these modern medicine and 36 00:01:44,960 --> 00:01:44,970 against these modern medicine and 37 00:01:44,970 --> 00:01:48,200 against these modern medicine and pharmacology have focused more on the 38 00:01:48,200 --> 00:01:48,210 pharmacology have focused more on the 39 00:01:48,210 --> 00:01:51,280 pharmacology have focused more on the microscopic than the macroscopic world 40 00:01:51,280 --> 00:01:51,290 microscopic than the macroscopic world 41 00:01:51,290 --> 00:01:55,280 microscopic than the macroscopic world it is in fact in this rearm that we can 42 00:01:55,280 --> 00:01:55,290 it is in fact in this rearm that we can 43 00:01:55,290 --> 00:01:58,430 it is in fact in this rearm that we can better understand and hence defeat the 44 00:01:58,430 --> 00:01:58,440 better understand and hence defeat the 45 00:01:58,440 --> 00:02:03,380 better understand and hence defeat the enemy in fact the more precisely we know 46 00:02:03,380 --> 00:02:03,390 enemy in fact the more precisely we know 47 00:02:03,390 --> 00:02:05,870 enemy in fact the more precisely we know the protein structure of of a disease or 48 00:02:05,870 --> 00:02:05,880 the protein structure of of a disease or 49 00:02:05,880 --> 00:02:09,650 the protein structure of of a disease or a parasite the more effectively the 50 00:02:09,650 --> 00:02:09,660 a parasite the more effectively the 51 00:02:09,660 --> 00:02:11,750 a parasite the more effectively the weekend engineer drugs and medications 52 00:02:11,750 --> 00:02:11,760 weekend engineer drugs and medications 53 00:02:11,760 --> 00:02:18,500 weekend engineer drugs and medications or vaccines to counteract them if we 54 00:02:18,500 --> 00:02:18,510 or vaccines to counteract them if we 55 00:02:18,510 --> 00:02:21,020 or vaccines to counteract them if we were able to transport ourselves to the 56 00:02:21,020 --> 00:02:21,030 were able to transport ourselves to the 57 00:02:21,030 --> 00:02:24,470 were able to transport ourselves to the microscopic world we would find that 58 00:02:24,470 --> 00:02:24,480 microscopic world we would find that 59 00:02:24,480 --> 00:02:27,800 microscopic world we would find that this proteins look very much like this 60 00:02:27,800 --> 00:02:27,810 this proteins look very much like this 61 00:02:27,810 --> 00:02:36,890 this proteins look very much like this model right here 62 00:02:36,890 --> 00:02:36,900 63 00:02:36,900 --> 00:02:43,179 who are in fact three-dimensional 64 00:02:43,179 --> 00:02:43,189 65 00:02:43,189 --> 00:02:46,780 arranged in very specific patterns 66 00:02:46,780 --> 00:02:46,790 arranged in very specific patterns 67 00:02:46,790 --> 00:02:51,080 arranged in very specific patterns booking structures present very specific 68 00:02:51,080 --> 00:02:51,090 booking structures present very specific 69 00:02:51,090 --> 00:02:53,899 booking structures present very specific notes and crannies to which other 70 00:02:53,899 --> 00:02:53,909 notes and crannies to which other 71 00:02:53,909 --> 00:02:57,140 notes and crannies to which other proteins bind and relate to their 72 00:02:57,140 --> 00:02:57,150 proteins bind and relate to their 73 00:02:57,150 --> 00:03:00,649 proteins bind and relate to their surroundings these lands are binding 74 00:03:00,649 --> 00:03:00,659 surroundings these lands are binding 75 00:03:00,659 --> 00:03:04,250 surroundings these lands are binding sides hold the key to many of the 76 00:03:04,250 --> 00:03:04,260 sides hold the key to many of the 77 00:03:04,260 --> 00:03:05,839 sides hold the key to many of the critical functions of the living 78 00:03:05,839 --> 00:03:05,849 critical functions of the living 79 00:03:05,849 --> 00:03:09,289 critical functions of the living organisms inhibiting some of the sides 80 00:03:09,289 --> 00:03:09,299 organisms inhibiting some of the sides 81 00:03:09,299 --> 00:03:14,030 organisms inhibiting some of the sides can alter can arrest can neutralize or 82 00:03:14,030 --> 00:03:14,040 can alter can arrest can neutralize or 83 00:03:14,040 --> 00:03:16,940 can alter can arrest can neutralize or in fact in the case of a disease can 84 00:03:16,940 --> 00:03:16,950 in fact in the case of a disease can 85 00:03:16,950 --> 00:05:51,740 in fact in the case of a disease can kill it 86 00:05:51,740 --> 00:05:51,750 87 00:05:51,750 --> 00:05:55,399 hello folks 88 00:05:55,399 --> 00:05:55,409 89 00:05:55,409 --> 00:05:57,619 Oh Jeff hi Claude we're looking in the 90 00:05:57,619 --> 00:05:57,629 Oh Jeff hi Claude we're looking in the 91 00:05:57,629 --> 00:07:56,020 Oh Jeff hi Claude we're looking in the window anga 92 00:07:56,020 --> 00:07:56,030 93 00:07:56,030 --> 00:08:02,830 columbia were handed over to Goldstone a 94 00:08:02,830 --> 00:08:02,840 95 00:08:02,840 --> 00:08:06,920 lot of the same columbia through 96 00:08:06,920 --> 00:08:06,930 lot of the same columbia through 97 00:08:06,930 --> 00:08:15,110 lot of the same columbia through gallstones okay and i got the big 98 00:08:15,110 --> 00:08:15,120 gallstones okay and i got the big 99 00:08:15,120 --> 00:08:18,610 gallstones okay and i got the big picture from rich when you ready to copy 100 00:08:18,610 --> 00:08:18,620 picture from rich when you ready to copy 101 00:08:18,620 --> 00:08:24,440 picture from rich when you ready to copy okay stories i have a picnic okay we 102 00:08:24,440 --> 00:08:24,450 okay stories i have a picnic okay we 103 00:08:24,450 --> 00:08:29,000 okay stories i have a picnic okay we will bring up edwards for tomorrow we 104 00:08:29,000 --> 00:08:29,010 will bring up edwards for tomorrow we 105 00:08:29,010 --> 00:08:32,680 will bring up edwards for tomorrow we will not attempt the first rev at KSC 106 00:08:32,680 --> 00:08:32,690 will not attempt the first rev at KSC 107 00:08:32,690 --> 00:08:39,230 will not attempt the first rev at KSC that's on orbit 234 we will take aim at 108 00:08:39,230 --> 00:08:39,240 that's on orbit 234 we will take aim at 109 00:08:39,240 --> 00:08:42,140 that's on orbit 234 we will take aim at the second opportunity at KSC which is 110 00:08:42,140 --> 00:08:42,150 the second opportunity at KSC which is 111 00:08:42,150 --> 00:08:47,540 the second opportunity at KSC which is 235 if we waive off on that one we will 112 00:08:47,540 --> 00:08:47,550 235 if we waive off on that one we will 113 00:08:47,550 --> 00:08:52,880 235 if we waive off on that one we will evaluate 236 at KSC we will also 114 00:08:52,880 --> 00:08:52,890 evaluate 236 at KSC we will also 115 00:08:52,890 --> 00:08:58,730 evaluate 236 at KSC we will also evaluate 236 at edwards if we waive off 116 00:08:58,730 --> 00:08:58,740 evaluate 236 at edwards if we waive off 117 00:08:58,740 --> 00:09:01,270 evaluate 236 at edwards if we waive off of KSC will take a hard look at 118 00:09:01,270 --> 00:09:01,280 of KSC will take a hard look at 119 00:09:01,280 --> 00:09:05,810 of KSC will take a hard look at Saturday's weather at KSC and we will 120 00:09:05,810 --> 00:09:05,820 Saturday's weather at KSC and we will 121 00:09:05,820 --> 00:09:08,960 Saturday's weather at KSC and we will keep that option open for a Saturday 122 00:09:08,960 --> 00:09:08,970 keep that option open for a Saturday 123 00:09:08,970 --> 00:09:13,130 keep that option open for a Saturday landing at KSC so the first one we'll 124 00:09:13,130 --> 00:09:13,140 landing at KSC so the first one we'll 125 00:09:13,140 --> 00:09:16,670 landing at KSC so the first one we'll try is a second opportunity at KSC if we 126 00:09:16,670 --> 00:09:16,680 try is a second opportunity at KSC if we 127 00:09:16,680 --> 00:09:19,100 try is a second opportunity at KSC if we waive off there we'll look at the third 128 00:09:19,100 --> 00:09:19,110 waive off there we'll look at the third 129 00:09:19,110 --> 00:09:21,980 waive off there we'll look at the third opportunity at KSC and also look at 130 00:09:21,980 --> 00:09:21,990 opportunity at KSC and also look at 131 00:09:21,990 --> 00:09:24,410 opportunity at KSC and also look at edwards but we will keep our options 132 00:09:24,410 --> 00:09:24,420 edwards but we will keep our options 133 00:09:24,420 --> 00:09:27,950 edwards but we will keep our options open if it is optimistic for Saturday 134 00:09:27,950 --> 00:09:27,960 open if it is optimistic for Saturday 135 00:09:27,960 --> 00:09:35,170 open if it is optimistic for Saturday landing at KSC will try that also okay 136 00:09:35,170 --> 00:09:35,180 landing at KSC will try that also okay 137 00:09:35,180 --> 00:09:37,970 landing at KSC will try that also okay forecaster Saturday they had to pick 138 00:09:37,970 --> 00:09:37,980 forecaster Saturday they had to pick 139 00:09:37,980 --> 00:09:42,550 forecaster Saturday they had to pick innocent Edwards on that second dress 140 00:09:42,550 --> 00:09:42,560 141 00:09:42,560 --> 00:09:44,900 yes sir the second or the third 142 00:09:44,900 --> 00:09:44,910 yes sir the second or the third 143 00:09:44,910 --> 00:09:48,130 yes sir the second or the third opportunity at Edwards that's to 36 or 144 00:09:48,130 --> 00:09:48,140 opportunity at Edwards that's to 36 or 145 00:09:48,140 --> 00:09:52,580 opportunity at Edwards that's to 36 or 237 so if this saturday forecast is 146 00:09:52,580 --> 00:09:52,590 237 so if this saturday forecast is 147 00:09:52,590 --> 00:09:55,670 237 so if this saturday forecast is really poor for KSC the chances are you 148 00:09:55,670 --> 00:09:55,680 really poor for KSC the chances are you 149 00:09:55,680 --> 00:10:07,320 really poor for KSC the chances are you go to edwards on to 36 or 237 okay 150 00:10:07,320 --> 00:10:07,330 151 00:10:07,330 --> 00:10:11,019 and I've got some proposed sleep times 152 00:10:11,019 --> 00:10:11,029 and I've got some proposed sleep times 153 00:10:11,029 --> 00:10:18,610 and I've got some proposed sleep times for you have a copy if the blue is a the 154 00:10:18,610 --> 00:10:18,620 for you have a copy if the blue is a the 155 00:10:18,620 --> 00:10:20,440 for you have a copy if the blue is a the blue team's not in bed they can be a 156 00:10:20,440 --> 00:10:20,450 blue team's not in bed they can be a 157 00:10:20,450 --> 00:10:24,850 blue team's not in bed they can be a hidden that way about now we're 158 00:10:24,850 --> 00:10:24,860 hidden that way about now we're 159 00:10:24,860 --> 00:10:28,120 hidden that way about now we're proposing your sleep read sleep at 14 160 00:10:28,120 --> 00:10:28,130 proposing your sleep read sleep at 14 161 00:10:28,130 --> 00:10:32,260 proposing your sleep read sleep at 14 days two hours and 45 minutes proposing 162 00:10:32,260 --> 00:10:32,270 days two hours and 45 minutes proposing 163 00:10:32,270 --> 00:10:36,940 days two hours and 45 minutes proposing blue to be up at 14 days two hours in a 164 00:10:36,940 --> 00:10:36,950 blue to be up at 14 days two hours in a 165 00:10:36,950 --> 00:10:40,810 blue to be up at 14 days two hours in a 30 minutes and you all read to be up at 166 00:10:40,810 --> 00:10:40,820 30 minutes and you all read to be up at 167 00:10:40,820 --> 00:10:45,640 30 minutes and you all read to be up at 14 days 10 hours and 45 minutes